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Magic Mushrooms And Psilocybin
Psilocybin is a hallucinogenic chemical in certain mushrooms that grow in Europe, South America, Mexico, and the United States. Mushrooms that contain psilocybin are known as magic mushrooms.
Individuals use psilocybin as a recreational drug. It can provide feelings of euphoria and sensory distortion that are common to hallucinogenic drugs, such as LSD.
Researchers at Johns Hopkins Center for Psychedelic and Consciousness Research published a landmark studyTrusted Source on the safety and positive effects of psilocybin in 2006. Researchers have also investigated whether it may be used to treat various medical conditions.
In October 2020, Oregon became the first state to legalize psilocybin. This allows for a 2-year period to consider regulatory and prescribing requirements.
Psilocybin is a Schedule I substance, meaning that the Drug Enforcement Administration (DEA) believes it has a high potential for abuse and serves no legitimate medical purpose.
How it works
Psilocybin works by activating serotonin receptors, most often in the prefrontal cortex. This part of the brain affects mood, cognition, and perception. Hallucinogens also work in other regions of the brain that regulate arousal and panic responses.
Psilocybin does not always cause active visual or auditory hallucinations. Instead, it distorts how some people that use the drug perceive objects and people already in their environment.
The quantity of the drug a person consumes, their past experiences, and their expectations of how the experience will take shape can all impact the effects of psilocybin.
The hallucinogenic effects of psilocybin usually occur within 30 minutes after a person ingests it and last 4–6 hours. In some individuals, changes in sensory perception and thought patterns can last for several days.
he potency of a magic mushroom depends on:
- growing conditions
- harvest period
- whether a person eats them fresh or dried
Physical health risks Of Magic Mushrooms
Psilocybin effects are similar to those of other hallucinogens, such as mescaline from peyote or LSD. The psychological reaction to psilocybin use include visual and auditory hallucinations and an inability to discern fantasy from reality. Panic reactions and psychosis also may occur, particularly if large doses of psilocybin are ingested.
Hallucinogens that interfere with the action of the brain chemical serotonin may alter:
- sensory perception
- body temperature
- sexual behavior
- muscle control
Physical effects of psychedelic mushrooms may include a feeling of nausea, vomiting, muscle weakness, confusion, and a lack of coordination. Combined use with other substances, such as alcohol and marijuana can heighten, or worsen all of these effects.
Other effects of hallucinogenic drugs can include:
- intensified feelings and sensory experiences
- changes in sense of time (for example, time passing by slowly)
- increased blood pressure, breathing rate, or body temperature
- loss of appetite
- dry mouth
- sleep problems
- mixed senses (such as “seeing” sounds or “hearing” colors)
- spiritual experiences
- feelings of relaxation or detachment from self/environment
- uncoordinated movements
- lowered inhibition
- excessive sweating
- paranoia – extreme and unreasonable distrust of others
- psychosis – disordered thinking detached from reality
Larger psilocybin doses, including an overdose, can lead to intense hallucinogenic effects over a longer period of time. An intense “trip” episode may occur, which may involve panic, paranoia, psychosis, frightful visualizations (“bad trip”), and very rarely death. Memory of a “bad trip” can last a lifetime.
Abuse of psilocybin mushrooms could also lead to toxicity or death if a poisonous mushroom is incorrectly thought to be a “magic” mushroom and ingested. If vomiting, diarrhea, or stomach cramps begin several hours after consuming the mushrooms, the possibility of poisoning with toxic mushrooms should be considered, and emergency medical care should be sought immediately.
Tolerance to the use of psilocybin has been reported, which means a person needs an increasing larger dose to get the same hallucinogenic effect. “Flashbacks”, similar to those occur in some people after using LSD, have also been reported with mushrooms. It is reported that people who use LSD or mescaline can build a cross-tolerance to psilocybin, as well. psilocybe mexicana
Common hallucinogens, with the possible exception of phencyclidine (PCP), are not usually tested for on standard workplace drug screens. However, if desired by legal authorities, medical personnel, or an employer, it is possible to perform laboratory assays that can detect any drug or metabolite, including psilocybin, via advanced techniques.
When tested via urine, the psilocybin mushroom metabolite psilocin can stay in your system for up to 3 days. However, metabolic rate, age, weight, age, medical conditions, drug tolerance, other drugs or medications used, and urine pH of each individual may affect actual detection periods.
Based on a 2018 survey from SAMHSA’s National Survey on Drug Use and Health (NSDUH), about 5.6 million people aged 12 or older reported using hallucinogens (which may include psilocybin mushrooms) in the year prior to the survey. In 2017, that number was roughly 5.1 million. In the survey, hallucinogens include not only psilocybin from mushrooms, but also other psychedelic drugs like LSD, MDMA (Ecstasy, Molly), and peyote (mescaline). In comparison, 43.5 million people used marijuana in the year prior to the 2018 survey.
In 2018, there were 1.1 million people aged 12 and older who had used hallucinogens for the first time within the past year. In particular, college students, and people ages 18 to 25, may choose mushrooms as a drug of abuse.